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Cristina Alexandre 

Postdoctoral Researcher

Research Interests:

I am interested in the impact of transcriptional noise on phenotypic plasticity. I focus on hypocotyl length in Arabidopsis, a streamlined quantitative model for environmentally-induced plasticity. Employing isogenic populations, I am (1) dissecting the sources of variance in hypocotyl length, (2) searching for purveyors of increased variance and (3) testing whether stochastic gene expression fluctuations in cell-autonomous pathways can shape whole-organism developmental outcomes.

Education:

  • 2011 Ph.D. in Plant Sciences, ETH Zürich, Switzerland Group of Plant Biotechnology, Prof. Dr. Wilhelm Gruissem
  • 2006 Post-graduation in Molecular Biology, University of Lisbon, Portugal
  • 2005 Licenciatura in Cell Biology and Biotechnology, University of Lisbon, Portugal

Experience:

  • 2011 Conservation volunteer with loggerhead sea-turtles, Turtle Foundation, Boavista, Cape Verde Islands
  • 2010-2011 Research assistant, Group of Dr. Lars Hennig, ETH Zürich/SLU Uppsala, working on flower development in Arabidopsis
  • 2006-2010 Teaching assistant for Plant Biology and Epigenetics, ETH Zürich

Publications:

  • Alexandre CM, Urton JR, Jean-Baptiste K, Huddleston JL, Dorrity MW, Cuperus JT, Sullivan AM, Bemm F, Jolic D, Arsovski AA, Thompson A, Nemhauser JL, Fields S, Weigel D, Bubb KL, Queitsch C. Mol Biol Evol. 2017 Dec 20. doi: 10.1093/molbev/msx326.
  • Simkovà K, Moreau F, Pawlak P, Vriet C, Baruah A, Alexandre C, Hennig L, Apel K, Laloi C. (2012) Integration of stress-related and reactive oxygenspecies-mediated signals by Topoisomerase VI in Arabidopsis thaliana. PNAS 109(40):16360-5.
  • Exner V, Alexandre C, Rosenfeldt G, Alfarano P, Nater M, Caflisch A, Gruissem W, Batschauer A, Hennig L. (2010) A gain-of-function mutation of Arabidopsis cryptochrome1 promotes flowering. Plant Physiol 154(4):1633-45.
  • Alexandre, C.1, Möller-Steinbach, Y.1, Schönrock, N.1, Gruissem, W., Hennig, L. (2009) Arabidopsis MSI1 is required for negative regulation of the response to drought stress. Mol Plant 2(4), 675-687. 1contributed equally
  • Möller-Steinbach Y., Alexandre C., Hennig L. (2010) Flowering time control. Methods Mol Biol 655:229-37.
  • Alexandre, C. and Hennig, L. (2008) FLC or not FLC - the other side of vernalization. J Exp Bot 59(6),1127-1135.
  • Alexandre, C. and Hennig, L. (2007) FLC-independent vernalization responses. Intern J Plant Dev Biol 1, 202-211.

Contact Me:

alexcm (at) u.washington.edu

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